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Associate Scientific Director, Immunological Toxicology

Janssen Research and Development, L.L.C., a
member of Johnson and Johnson's Family of Companies, is recruiting for an Associate
Scientific Director, Immunological Toxicology located in Spring House, PA with
up to 20% travel.
At the Janssen Pharmaceutical Companies of
Johnson & Johnson, what matters most is helping people live full and
healthy lives. We focus on treating, curing and preventing some of the most
devastating and complex diseases of our time. And we pursue the most promising
science, wherever it might be found.
Janssen Research & Development, LLC
discovers and develops innovative medical solutions to address important unmet
medical needs in oncology, immunology, neuroscience, infectious diseases and
vaccines, and cardiovascular and metabolic diseases. Please visit
http://www.JanssenRnD.com for more information.
We are Janssen. Our mission drives us. Our
patients inspire us. We collaborate with the world for the health of everyone
in it.
Thriving on a diverse company culture,
celebrating the uniqueness of our employees and committed to inclusion. Proud
to be an equal opportunity employer.
The Associate Scientific Director,
Immunological Toxicology will evaluate potential immune system-related effects associated
with large and small molecule therapeutics in our pipeline. The Associate Scientific Director will work
with Project Toxicologists and nonclinical safety team to
provide strategic and scientific input ? to progress therapeutics from
discovery to first-in-human and through development. As an Associate Scientific
Director additional responsibility will include:
+ Provides
immunological expertise to nonclinical safety teams, designs strategies to
evaluate potential immunotoxicology risks, and participates in assessments. Strategies
will include literature evaluation, as well as, direct experimental approaches
performed in-house and at Contract Research Organizations (CROs).
+ Interacts
with CROs at multiple levels, including: transferring methods developed at
Janssen, monitoring CRO validations, and the monitoring of immune endpoints
during both GLP and non-GLP studies.
+ Independently
designs, conducts and leads studies to evaluate the effects of immunomodulatory
compounds using various in vivo and in vitro model systems including, but not
limited to, cytokine assessment, immune response, flow cytometry and functional
cell-based assays following Data Integrity standards, and writes reports for
regulatory submission.
+ Investigates
and develops novel experimental methods/technologies, contributes to
improvement of existing methods and develops new in vitro/in vivo models to
enhance our understanding of potential immunotoxicology risk and translatability
to humans in the clinic.
+ Participates
in communication of information and data presentation in oral and written
format both in-house and at appropriate external forums.
+ Maintains
an industry leading expertise in Immunotoxicology.
+ Represents
the organization to senior management and peer groups within Janssen and
Johnson & Johnson.
+ Maintains
strong scientific network in academia and the pharmaceutical/biotechnology
industry to enable external interactions, consulting and recruiting.
+ Be a
mentor/coach to key scientific staff and guide/enable their career/professional
development.
+ Responsible
for the development of all employees within the department by supporting the
development of Human Resources Planning (HRP) programs including management
development and training to meet current and future business needs.
+ Provide
an environment, which encourages the company's commitment to equal employment
opportunity and the value of a diverse work force.
Qualifications
+ PhD in immunology, immunotoxicology, toxicology or related
discipline with 3 years of relevant experience OR M.S. degree in immunology,
immunotoxicology, toxicology or related discipline with 7 years of relevant
experience OR a professional degree (DVM, VMD) with 3 years of relevant
experience is required
+ Established expertise in
Immunotoxicology is required
+ Expertise in immunological techniques
(e.g. flow cytometry, immunoassays) is required
+ Deep scientific expertise in
immunology is preferred
+ Experience
in pharmaceutical/biotechnology research management or related experience in
drug development is required
+ Knowledge
of GLPs is required
+ Knowledge
of Health Authority regulations and guidelines for drug development (e.g. ICH,
FDA, EMEA, PMDA) is preferred
+ Previous
experience managing external partnerships (CRO?s) is required
+ Strong leadership skills with highly
collaborative instincts
+ This role requires excellent
communication and interpersonal skills, a high level of organizational ability
and attention to detail
Primary Location
United States-Pennsylvania-Spring House-1400?McKean?Road
Organization
Janssen Research & Development, LLC. (6084)
Job Function
Toxicology Research
Requisition ID
3859180612

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